Funded Research

Funded // 2018–2019 Funding Round

Role of innate immunity in impaired neurodevelopment during zika virus infection

We will study neuroprogenitors by intraventricular injection of ZIKV into fetus of pregnant mice. We will assess the inflammatory signaling with high-throughput protein kinase/phosphatase assay.
Trio Funded
Funded // 2018–2019 Funding Round

Isolation and analysis of patient-derived malaria parasites

This project will generate new tools for the characterization of malaria parasites directly from the bloodstream of patients.
Parasitology
Trio Funded
Funded // 2018–2019 Funding Round

Long-term Effects on Astronaut Bone Health after Space Flight

This study will collect and analyze the relevant data from the LSAH in order to evaluate the long-term health risks associated with space flight.
Biostatistics (Public Health); Biomechanics
Trio Funded
Funded // 2018–2019 Funding Round

The effects of oral inorganic nitrate supplementation on lower limb perfusion and metabolism during exercise in patients with Peripheral Arterial Disease (PAD)

To determine mechanisms of ambulation improvements in PAD+IC following inorganic nitrate supplementation by performing graded plantar flexion exercise while undergoing magnetic resonance imaging
Biomedical Engineering and Bioengineering; Cardiovascular Medicine; Exercise Physiology
Trio Funded
Funded // 2018–2019 Funding Round

Extracellular life style of an intracellular pathogen

We will test the hypothesis that before reaching the colon where it is an intracellular pathogen, S. flexneri develops an extracellular life style relying on biofilm formation in the small intestine.
Trio Funded
Funded // 2018–2019 Funding Round

Changing Through Subtraction

When people think about changing or improving something, do they add or subtract from what already exists?
Trio Funded
Funded // 2018–2019 Funding Round

The Impact of the Affordable Care Act’s dependent mandate on people living with HIV

This project will use econometrics methods to investigate the effects of the Affordable Care Act’s dependent mandate on HIV viral suppression for people living with HIV ages 23-28 in Virginia.
Public Health; Epidemiology; Econometrics; Public Policy
Trio Funded
Funded // 2018–2019 Funding Round

Neuromuscular pedicle for improved functional outcome of novel muscle regeneration scaffolds.

We aim to generate clinical functional recovery after volumetric muscle loss by combining a neuromuscular pedicle embedded into novel scaffolds to provide regenerative cells and paracrine signaling.
Biomedical Engineering and Bioengineering; Biotechnology; Biomaterials
Trio Funded
Funded // 2018–2019 Funding Round

Engineering Cell-adhesive Microparticle Systems to Enable in vitro Modeling of Mammalian Neural Development

Collaborative work in between the chemical engineering and cell biology departments will identify conditions to build an in vitro model to study normal and pathological neural development
Developmental Biology; Molecular, Cellular, and Tissue Engineering
Trio Funded
Funded // 2018–2019 Funding Round

Genetic Dissection of Vagal Motor Circuits Controlling Heart Function

Our project will define the synaptic circuitry and functional role of three novel neuron types in the nucleus ambiguous, the major parasympathetic input to the cardiovascular and respiratory systems.
Neuroscience and Neurobiology; Behavioral Neurobiology
Trio Funded
Funded // 2018–2019 Funding Round

Palladio’s Villa La Rotonda: a Prototypical Site for Cultural Heritage Documentation and Scholarship

This effort will focus on Andrea Palladio's Villa La Rotonda (1566-71) as a prototype for the process of documentation, archiving, and scholarly analysis of cultural heritage landscapes.
Ancient, Medieval, Renaissance and Baroque Art and Architecture
Trio Funded
Funded // 2018–2019 Funding Round

Brain Mechanisms of Pain Fear Acquisition and Extinction in Humans

Using intracranial recordings from patients with epilepsy, we aim to explore the brain mechanisms supporting pain-related fear acquisition and extinction
Systems Neuroscience
Trio Funded