Funded Research

Funded // 2018–2019 Funding Round

Small molecule inhibitors of the CXXC domain, an epigenetic reader of DNA methylation

The CXXC domain functions as a reader of DNA methylation, binding to non-methylated CpGs. We will develop small molecule inhibitors and test effects on DNA methylation and growth of leukemia cells.
Medicinal-Pharmaceutical Chemistry
Trio Funded
Funded // 2018–2019 Funding Round

Modeling cerebral reperfusion injury using photoacoustic microscopy and oxygen-sensing nanoparticles

This project explores a novel non-invasive, dynamic imaging approach capable of quantifying functional changes in the brain following reperfusion after stroke.
Trio Funded
Funded // 2018–2019 Funding Round

A systems approach to understanding a neuronal circuit for detecting motion

Fruit fly larvae develop a simple learned visual recognition system to determine membership in cooperative feeding groups and we propose to study the underlying neural circuit.
Neuroscience and Neurobiology
Trio Funded
Funded // 2018–2019 Funding Round

Development of Smart Algorithm for Cardiac Device Discrimination of Arrhythmias to Deliver Personalized Therapy

This project aims to develop an algorithm for defibrillators to recognize arrhythmias from upper and lower chambers of the heart to customize device interventions.
Trio Funded
Funded // 2018–2019 Funding Round

Quantitative MRI of body fat and risk of cardiometabolic diseases

Obesity and association with risk of cardiometabolic diseases including type 2 diabetes (T2D) and atherosclerosis.
Trio Funded
Funded // 2018–2019 Funding Round

Genetic modification of dietary effects on nutrient distribution and metabolism

The aim of the project is to investigate effects of different diets on nutrient distribution and metabolism in key metabolic tissues and evaluate how individuals' genetic backgrounds modify effects.
Genetics and Genomics; Endocrinology; Systems and Integrative Physiology; Nutrition
Trio Funded
Funded // 2018–2019 Funding Round

Civil War Era Readers and their Books in Virginia Libraries

Discovery of and research upon previously-unnoticed marginalia in 19th-century books on academic library shelves in Virginia; emphasis on reading and memory in the Civil War era.
History; American Studies; American Material Culture; Literature in English, North America (other than ethnic and minority); Literature in English, North America, ethnic and minority
Trio Funded
Funded // 2018–2019 Funding Round

The Changing Face of Race: New Black Immigrants in American Public Schools

This project explores the experiences of new black immigrants from Africa and the Caribbean in US public schools as a window on contemporary processes of racialization in American public life.
Anthropology; Race and Ethnicity; Education
Trio Funded
Funded // 2018–2019 Funding Round

Designing Urban Space for Access and Memory

This study examines imposed inequities of urban design and governance decisions—buildings, roads, spaces, transit, walls, fences, regulations--that thwart social, political, and economic integration.
Urban Studies and Planning
Trio Funded
Funded // 2018–2019 Funding Round

Multifunctional Next Generation Energy Storage

This project will develop high-performance next generation batteries towards multifunctional applications of providing both mechanical support and electrochemical energy storage and delivery.
Chemical Engineering; Materials Chemistry; Structures and Materials (Aerospace Engineering); Power and Energy; Ceramic Materials; Energy Systems
Trio Funded
Funded // 2018–2019 Funding Round

The Moderating Effects of structured versus case Interviews on Candidate Rapport-Building Impressions and Outcomes

We will examine the efficacy of case interview beyond traditional interviews, through lab and field experiments. We will also support a PhD student's dissertation and undergrad RAs with the funds.
Social and Behavioral Sciences; Industrial and Organizational Psychology
Trio Funded
Funded // 2018–2019 Funding Round

Climate Resilience in Small Island Developing States – Case Study in Dominica

We will conduct research into climate resilience at the nexus of food, water and energy within the microcosm of Dominica, a small island developing state as a case study.
Economics; Environmental Engineering; Environmental Sciences; Systems Engineering and Multidisciplinary Design Optimization; Resilience
Trio Funded